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1

Science Fictions: A Scientific Mystery, a Massive Cover-up, and the Dark Legacy of Robert Gallo

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 527 KB

english, 2002

2

Renew, reduce or become more efficient? The climate contribution of biomass co-combustion in a coal-fired power plant

Miedema, Jan H., Benders, René M.J., Moll, Henri C., Pierie, Frank

Journal:

Year:

2016

Language:

english

File:

PDF, 2.67 MB

english, 2016

3

AIDS pathogenesis: a dynamic interaction between HIV and the immune system

Frank Miedema, Matthijs Tersmette, RenéA.W van Lier

Journal:

Immunology Today

Year:

1990

Language:

english

File:

PDF, 1.15 MB

english, 1990

4

Immune dysregulation and CD4+T cell loss in HIV-1 infection

Linde Meyaard, Frank Miedema

Journal:

Seminars in Immunopathology

Year:

1997

Language:

english

File:

PDF, 1.35 MB

english, 1997

5

T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation

Mette D. Hazenberg, Martie C. Verschuren, Dörte Hamann, Frank Miedema, Jacques J. Dongen

Journal:

Journal of Molecular Medicine

Year:

2001

Language:

english

File:

PDF, 184 KB

english, 2001

6

Thymic output: a bad TREC record

Hazenberg, Mette D., Borghans, José A.M., de Boer, Rob J., Miedema, Frank

Journal:

Nature Immunology

Year:

2003

Language:

english

File:

PDF, 58 KB

english, 2003

7

Long-term road traffic noise exposure is associated with an increase in morning tiredness

de Kluizenaar, Yvonne, Janssen, Sabine A., van Lenthe, Frank J., Miedema, Henk M. E., Mackenbach, Johan P.

Journal:

The Journal of the Acoustical Society of America

Year:

2009

Language:

english

File:

PDF, 300 KB

english, 2009

8

Urban road traffic noise and annoyance: The effect of a quiet façade

Kluizenaar, Yvonne de, Salomons, Erik M., Janssen, Sabine A., van Lenthe, Frank J., Vos, Henk, Zhou, Han, Miedema, Henk M. E., Mackenbach, Johan P.

Journal:

The Journal of the Acoustical Society of America

Year:

2011

Language:

english

File:

PDF, 530 KB

english, 2011

9

Governing Urban Regeneration: the Case of Rotterdam

GERARD OUDE ENGBERINK and FRANK MIEDEMA

Journal:

Geographische Zeitschrift

Year:

2001

Language:

english

File:

PDF, 1.48 MB

english, 2001

10

Residential Traffic and Pregnancy-Related Outcomes in Mother and Child: The Generation R Study

van den Hooven, Edith H., Jaddoe, Vincent W.V., de Kluizenaar, Yvonne, Hofman, Albert, Steegers, Eric A.P., Miedema, Henk M.E., Pierik, Frank H.

Journal:

Year:

2009

Language:

english

File:

PDF, 8.48 MB

english, 2009

11

Assessing scientists for hiring, promotion, and tenure

Moher, David, Naudet, Florian, Cristea, Ioana A., Miedema, Frank, Ioannidis, John P. A., Goodman, Steven N.

Journal:

Year:

2018

Language:

english

File:

PDF, 1002 KB

english, 2018

12

Fewer numbers, better science

Benedictus, Rinze, Miedema, Frank, Ferguson, Mark W. J.

Journal:

Year:

2016

File:

PDF, 1.07 MB

2016

13

High viral burden in the presence of major HIV-specific CD8+ T cell expansions: evidence for impaired CTL effector function

Stefan Kostense, Graham S. Ogg, Erik H. Manting, Geraldine Gillespie, Jeanine Joling, Kristin Vandenberghe, Eveline Z. Veenhof, Debbie van Baarle, Suzanne Jurriaans, Michèl R. Klein, Frank Miedema

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 210 KB

english, 2001

14

Functional restoration of human immunodeficiency virus and Epstein-Barr virus-specific CD8+ T cells during highly active antiretroviral therapy is associated with an increase in CD4+ T cells

Stefan Kostense, Sigrid A. Otto, Gerlinde J. Knol, Erik H. Manting, Nening M. Nanlohy, Christine Jansen, Joep M. A. Lange, Marinus H. J. van Oers, Frank Miedema, Debbie van Baarle

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 189 KB

english, 2002

15

Both Fc receptors and lymphocyte-function-associated antigen 1 on human Tγ lymphocytes are required for antibody-dependent cellular cytotoxicity (killer cell activity)

Frank Miedema, Pedro A. T. Tetteroo, Wim G. Hesselink, Guy Werner, Hergen Spits, Cornelis J. M. Melief

Journal:

European Journal of Immunology

Year:

1984

Language:

english

File:

PDF, 661 KB

english, 1984

16

Induction of immunoglobulin synthesis by interleukin 2 is T4+/T8− cell dependent. A role for interleukin 2 in the pokeweed mitogen-driven system

Frank Miedema, Johan W. Van Oostveen, Robert W. Sauerwein, Fokke G. Terpstra, Lucien A. Aarden, Cornelis J. M. Melief

Journal:

European Journal of Immunology

Year:

1985

Language:

english

File:

PDF, 642 KB

english, 1985

17

Biochemical and functional characteristics of the human leukocyte membrane antigen family LFA-1, Mo-1 and p!50,95

Gerrit D. Keizer, Jannie Borst, Carl G. Figdor, Hergen Spits, Frank Miedema, Cox Terhorst, Jan E. de Vries

Journal:

European Journal of Immunology

Year:

1985

Language:

english

File:

PDF, 857 KB

english, 1985

18

Anti-HLA-class II monoclonal antibodies inhibit polyclonal B cell differentiation in vitro at the accessory cell level

Menno A. De Rie, Peter Kabel, Robert W. Sauerwein, Rene A. W. Van Lier, Albert E. G. Kr. von Dem Borne, Cornelis J. M. Melief, Frank Miedema

Journal:

European Journal of Immunology

Year:

1987

Language:

english

File:

PDF, 612 KB

english, 1987

19

Anti-CD3 antibodies induce T helper function for human B cell differentiation in vitro by an interleukin 2-independent pathway

Robert W. Sauerwein, Walter G. J. Der Van Meer, Johan W. Van Oostveen, Frank Miedema, Lucien A. Aarden

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 508 KB

english, 1988

20

Anti-CD27 monoclonal antibodies identify two functionally distinct subpopulations within the CD4+ T cell subset

René A. W.Van Lier, Marco Oudkerk Pool, Peter Kabel, Saskia Mous, Fokke Terpstra, Menno A.De Rie, Cornelis J. M. Melief, Frank Miedema

Journal:

European Journal of Immunology

Year:

1988

Language:

english

File:

PDF, 683 KB

english, 1988

21

Longitudinal study of leukocyte functions in homosexual men seroconverted for HIV: rapid and persistent loss of B cell function after HIV infection

Fokke G. Terpstra, Bert J. M. Al, Marijke T. H. L. Roos, Frank De Wolf, Jaap Goudsmit, Peter T. H. A. Schellekens, Frank Miedema

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 674 KB

english, 1989

22

Selective loss of T cell functions in different stages of HIV infection Early loss ofanti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS

Rob A. Gruters, Fokke G. Terpstra, Rolien de Jong, Carel J. M. Van Noesel, René A. W. Van Lier, Frank Miedema

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 842 KB

english, 1990

23

Non-mitogenic T cell activation signals are sufficient for induction of human immunodeficiency virus transcription

Rob A. Gruters, Sigrid A. Otto, Bert J. M. Al, Arthur J. Verhoeven, Cornelis L. Verweij, René A. W. Van Lier, Frank Miedema

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 608 KB

english, 1991

24

Allo-cross-reactivity of a human neuraminidase-specific T cell clone dependent on presentation of an endogenous B cell-specific antigen

Karel C. Kuijpers, Pammy Treep-Van Leeuwen, Frank Miedema, Cornells J. Lucas

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 797 KB

english, 1991

25

The CD27− subset of peripheral blood memory CD4+ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo

Rolien de Jong, Miranda Brouwer, Berend Hooibrink, Tineke van der Pouw-Kraan, Frank Miedema, René A. W. van Lier

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 729 KB

english, 1992

26

HLA class I and II molecules present influenza virus antigens with different kinetics

Karel C. Kuijpers, Folkert J. Van Kemenade, Berend Hooibrink, Jacques J. Neefjes, Cees J. Lucas, René A. W. Van Lier, Frank Miedema

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 823 KB

english, 1992

27

Effects of HIV-1 Tat protein on human T cell proliferation

Linde Meyaard, Sigrid A. Otto, Hanneke Schuitemaker, Frank Miedema

Journal:

European Journal of Immunology

Year:

1992

Language:

english

File:

PDF, 477 KB

english, 1992

28

Skewing to the LFA-3 adhesion pathway by influenza infection of antigen-presenting cells

Folkert J. Van Kemenade, Karel C. Kuijpers, René de Waal-Malefijt, René A. W. Van Lier, Frank Miedema

Journal:

European Journal of Immunology

Year:

1993

Language:

english

File:

PDF, 527 KB

english, 1993

29

Evidence for intact costimulation via CD28 and CD27 molecules in hyporesponsive T cells from human immunodeficiency virus-infected individuals

Linde Meyaard, Heleen Kuiper, Sigrid A. Otto, Katja C. Wolthers, René A. W. van Lier, Frank Miedema

Journal:

European Journal of Immunology

Year:

1995

Language:

english

File:

PDF, 640 KB

english, 1995

30

Increased expression of CD80, CD86 and CD70 on T cells from HIV-infected individuals upon activation in vitro: regulation by CD4+ T cells

Katja C. Wolthers, Sigrid A. Otto, Susanne M. A. Lens, Dinanda N. Kolbach, René A. W. van Lier, Frank Miedema, Linde Meyaard

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 770 KB

english, 1996

31

High responsiveness of HLA-B57-restricted Gag-specific CD8+ T cells in vitro may contribute to the protective effect of HLA-B57 in HIV-infection

Christine A. Jansen, Stefan Kostense, Kristin Vandenberghe, Nening M. Nanlohy, Iris M. De Cuyper, Erwan Piriou, Erik H. Manting, Frank Miedema, Debbie van Baarle

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 300 KB

english, 2005

32

Limited role for the thymus in SIV pathogenesis

José A. M. Borghans, Mette D. Hazenberg, Frank Miedema

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 92 KB

english, 2005

33

Novel method for detection of virus-specific CD4+ T cells indicates a decreased EBV-specific CD4+ T cell response in untreated HIV-infected subjects

Erwan R. Piriou, Karel van Dort, Nening M. Nanlohy, Marinus H. van Oers, Frank Miedema, Debbie van Baarle

Journal:

European Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 324 KB

english, 2005

34

T-cell regulation of human B-cell activation. A reappraisal of the role of interleukin 2

Frank Miedema, Cornelis J.M. Melief

Journal:

Immunology Today

Year:

1985

Language:

english

File:

PDF, 190 KB

english, 1985

35

T-cell dysfunction in HIV infection: anergy due to defective antigen-presenting cell function?

Linde Meyaard, Hanneke Schuitemaker, Frank Miedema

Journal:

Immunology Today

Year:

1993

Language:

english

File:

PDF, 537 KB

english, 1993

36

Comment on Mosier and Sieburg

Hanneke Schuitemaker, Frank Miedema

Journal:

Immunology Today

Year:

1995

Language:

english

File:

PDF, 342 KB

english, 1995

37

Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system

Debbie van Baarle, Aster Tsegaye, Frank Miedema, Arne Akbar

Journal:

Immunology Letters

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

38

Kinetics of immune functions and virus replication during HIV-1 infection

Oscar Pontesilli, Michèl R Klein, Susana R Kerkhof-Garde, Nadine G Pakker, Frank de Wolf, Hanneke Schuitemaker, Frank Miedema

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 169 KB

english, 1997

39

Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection

Oscar Pontesilli, Susana Kerkhof-Garde, Nadine G. Pakker, Daan W. Notermans, Marijke T.L. Roos, Michel R. Klein, Sven A. Danner, Frank Miedema

Journal:

Immunology Letters

Year:

1999

Language:

english

File:

PDF, 126 KB

english, 1999

40

Rapid CD4+ T-cell turnover in HIV-1 infection: A paradigm revisited

Katja C. Wolthers, Hanneke Schuitemaker, Frank Miedema

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 13.62 MB

english, 1998

41

European immunologists meet in Amsterdam

Hans Clevers, Frank Miedema

Journal:

Immunology Today

Year:

1997

Language:

english

File:

PDF, 149 KB

english, 1997

42

Cytotoxic T lymphocytes in HIV-1 infection: a killing paradox?

Michèl R Klein, Sjoerd H van der Burg, Oscar Pontesilli, Frank Miedema

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 200 KB

english, 1998

43

Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion

Elmar S. D. De Pauw, Sigrid A. Otto, Juul T. Wijnen, Jaak M. Vossen, Margreet H. Van Weel, Hans J. Tanke, Frank Miedema, Roel Willemze, Helene Roelofs, Willem E. Fibbe

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 256 KB

english, 2002

44

Low T-cell responsiveness to activation via CD3/TCR is a prognostic marker for acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus-1 (HIV-1)-infected men

Peter Th. A. Schellekens, Marijke Th. L. Roos, Frank Wolf, Joep M. A. Lange, Frank Miedema

Journal:

Journal of Clinical Immunology

Year:

1990

Language:

english

File:

PDF, 860 KB

english, 1990

45

Disagreement between subjective and actigraphic measures of sleep duration in a population-based study of elderly persons

JULIA F. VAN DEN BERG, FRANK J.A. VAN ROOIJ, HENK VOS, JOKE H.M. TULEN, ALBERT HOFMAN, HENK M.E. MIEDEMA, ARIE KNUISTINGH NEVEN, HENNING TIEMEIER

Journal:

Journal of Sleep Research

Year:

2008

Language:

english

File:

PDF, 112 KB

english, 2008

46

Changing Virus-Host Interactions in the Course of HIV-1 Infection

Frank Miedema, Linde Meyaard, Maarten Koot, Michel Klein, Marijke Th. L. Roos, Martlin Groenink, Ron A. M. Fouchier, Angélique B. Van't Wout, Matthus Tersmette, Peter Th. A. Schellekens, Hanneke Schui

Journal:

Immunological Reviews

Year:

1994

Language:

english

File:

PDF, 11.45 MB

english, 1994

47

Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase

Gruters, Rob A., Neefjes, Jacques J., Tersmette, Matthijs, de Goede, Ruud E. Y., Tulp, Abraham, Huisman, Han G., Miedema, Frank, Ploegh, Hidde L.

Journal:

Year:

1987

File:

PDF, 552 KB

1987

48

Regulatory properties of LFA-1 α and β chains in human T-lymphocyte activation

van Noesel, Carel, Miedema, Frank, Brouwer, Miranda, de Rie, Menno A., Aarden, Lucien A., van Lier, René A. W.

Journal:

Year:

1988

File:

PDF, 467 KB

1988

49

HIV tropism

Schuitemaker, Hanneke, Groenink, Martijn, Tersmette, Matthijs, Miedema, Frank

Journal:

Year:

1993

File:

PDF, 148 KB

1993

50

10.1038/79549

Miedema, Frank, Hazenberg, Mette D., Otto, Sigrid A., Stuart, James W.T. Cohen, Verschuren, Martie C.M., Borleffs, Jan C.C., Boucher, Charles A.B., Coutinho, Roel A., Lange, Joep M.A., de Wit, Tobias

Journal:

Nature Medicine

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000